BX inhibits Akt signaling, inducing apoptosis and suppressing tumor growth. Product Info. Cas No. Purity. ≥98%. BX is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1), as well as other kinases including TANK-binding kinase 1 (TBK1), Aurora B and IkB. BX is a potent PDK1 inhibitor. BX also suppresses MARK1, MARK2, MARK4, NUAK1, VEGFR, MLK1, MLK2, MLK3 with IC50 of 55, 53, 19, 5, , BX is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1), as well as other kinases including TANK-binding kinase 1 (TBK1), Aurora B and IkB kinase. The IUPHAR/BPS Guide to Pharmacology. BX ligand page.
BX hydrochloride | PDK1/TBK1 inhibitor | BX hydrochloride | BX hydrochloride | CAS [] - [] | Axon | Axon Ligand™ with. BX hydrochloride (N-[3-[[5-iodo[[3-[(2-thienylcarbonyl)amino]propyl]amino]pyrimidinyl]amino]phenyl]Pyrrolidinecarboxamide); >= 98% HPLC; BX BX is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDPK1). Inhibits Akt phosphorylation at Thr in PC3 cells; also inhibits anchorage-. ChemScene Provide BX (CAS ) In-stock or Backordered impurities, Bulk custom synthesis, Formular C23H26IN7O2S, MW bulk manufacturing. BX is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines. BX is an aminopyrimidine-based, ATP-competitive inhibitor of PDK1, TBK1, and IKKe, with IC50 values of 11 nM, 6 nM, and 41 nM, respectively. BX is a potent TBK1 inhibitor. Fully validated with Human TBK1 using the Transcreener ADP Assay. An IC50 of nM was obtained when tested in vitro. BX was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC50 = 11nM for PDK1) and has been shown to be a potent and relatively. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX also is a potent inhibitor of cell. BX is a potent and relatively specific PDK1 inhibitor with IC50 of 6 nM; also inhibits TBK1 and IKKε with IC50 of 6 nM and 41 nM.
Brand: InvivoGen. Storage Conditions: 20°C. Product Type: Inhibitors. Product Link: ccinfinitygame.online Related products. BX is a potent and specific PDK1 inhibitor with IC50 of 6 nM, and fold more selective for PDK1 than PKA and PKC in cell-free assays. BX BX, also referenced under CAS , modulates the biological activity of multiple kinases. This small molecule/inhibitor is primarily used. UN Number: Not dangerous goods · DMSO mg/mL ( mM) Water Insoluble Ethanol Insoluble · Storage Temp: 20°C · BX Read more · For research use only. BX is a potent inhibitor of the IkB kinases TANK-binding kinase 1. (TBK1) and IkappaB kinase-epsilon (IKKε). TBK1 and IKKε play a central role in the innate. BX is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC BX is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1;. BX, a small molecule with an aminopyrimidine backbone in its chemical structure, is a potent and ATP-competitive inhibitor of. View and buy high purity BX PDPK1 (PDK1) inhibitor. Cited in 3 publications.
BioCrick is a famous high-purity reference standards manufacturer. Our BX is confirmed by NMR. Order now can get a discount! BX is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC BX is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines. BX - CAS - Calbiochem BX, also referenced under CAS , modulates the biological activity of multiple kinases. BX , CAS: , is an inhibitor of PDK1, TBK1, and IKK&epsilon. MF: C23H26IN7O2S, MW: Cited in 9 publications.
learn python programming | wood beads